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Monday, May 18, 2009

General Instructions for Disposable Respirators



H1N1 Flu and Antiviral Drugs



WHO confirms 1,893 human A/H1N1 cases worldwide

GENEVA, (Xinhua) -- The World Health Organization (WHO) yesterday confirmed a total of 1,893 human infection cases of the A/H1N1 flu virus from 23 countries, including 31 deaths.

Mexico, the epicenter of the outbreak, has reported 942 laboratory-confirmed human cases of infection, including 29 deaths. The United States has reported 642 laboratory-confirmed human cases, including two deaths, the UN agency said in a latest update.

The following governments have reported laboratory-confirmed cases with no deaths: Austria (1), Canada (165), Hong Kong, China (1), Colombia (1), Costa Rica (1), Denmark (1), El Salvador (2), France (5), Germany (9), Guatemala (1), Ireland (1), Israel (4), Italy (5), the Netherlands (1), New Zealand (5), Portugal (1), the Republic of Korea (2), Spain (73), Sweden (1), Switzerland (1) and Britain (28).

Meanwhile, a WHO official said yesterday that an expert committee of the agency would meet next week to discuss issues related to the production of A/H1N1 vaccine.

The committee is expected to give advice to the WHO on whether the time has come for drug makers such as GlaxoSmithKline and Novartis to start large-scale manufacturing of the vaccine, Marie- Paule Kieny, WHO director of the Initiative for Vaccine Research, told a news briefing in Geneva.

Kieny added that WHO Director-general Margaret Chan and UN Secretary-general Ban Ki-moon would also meet with heads of a number of companies manufacturing vaccines on May 19, to "ensure more equitable access for developing countries to this vaccine when it is available.

17 May 2009 - Already 39 countries cases of influenza A(H1N1)

17 May 2009, 39 countries have officially reported 8480 cases of influenza A(H1N1) infection.

Mexico has reported 2895 laboratory confirmed human cases of infection, including 66 deaths. The United States has reported 4714 laboratory confirmed human cases, including four deaths. Canada has reported 496 laboratory confirmed human cases, including one death. Costa Rica has reported nine laboratory confirmed human cases, including one death.

The following countries have reported laboratory confirmed cases with no deaths - Argentina (1), Australia (1), Austria (1), Belgium (4), Brazil (8), China (5), Colombia (11), Cuba (3), Denmark (1), Ecuador (1), El Salvador (4), Finland (2), France (14), Germany (14), Guatemala (3), India (1), Ireland (1), Israel (7), Italy (9), Japan (7), Malaysia (2), Netherlands (3), New Zealand (9), Norway (2), Panama (54), Peru (1), Poland (1), Portugal (1), Republic of Korea (3), Spain (103), Sweden (3), Switzerland (1), Thailand (2), Turkey (1), and the United Kingdom (82).

WHO is not recommending travel restrictions related to the outbreak of the influenza A(H1N1) virus.

Individuals who are ill should delay travel plans and returning travelers who fall ill should seek appropriate medical care. These recommendations are prudent measures which can limit the spread of many communicable diseases, including influenza.

Further information on the situation will be available on the WHO web site on a regular basis.

Influenza A (H1N1)

A New Influenza Virus

Novel influenza A (H1N1) is a new flu virus of swine origin that was first detected in April, 2009. The virus is infecting people and is spreading from person-to-person, sparking a growing outbreak of illness in the United States. An increasing number of cases are being reported internationally as well.

It’s thought that novel influenza A (H1N1) flu spreads in the same way that regular seasonal influenza viruses spread; mainly through the coughs and sneezes of people who are sick with the virus.

It’s uncertain at this time how severe this novel H1N1 outbreak will be in terms of illness and death compared with other influenza viruses. Because this is a new virus, most people will not have immunity to it, and illness may be more severe and widespread as a result. In addition, currently there is no vaccine to protect against this novel H1N1 virus. CDC anticipates that there will be more cases, more hospitalizations and more deaths associated with this new virus in the coming days and weeks.

Novel influenza A (H1N1) activity is now being detected through CDC’s routine influenza surveillance systems and reported weekly in FluView. CDC tracks U.S. influenza activity through multiple systems across five categories. The fact that novel H1N1 activity can now be monitored through seasonal surveillance systems is an indication that there are higher levels of influenza-like illness in the United States than is normal for this time of year. About half of all influenza viruses being detected are novel H1N1 viruses.
CDC Response
CDC continues to take aggressive action to respond to the outbreak. CDC’s response goals are to reduce the spread and severity of illness, and to provide information to help health care providers, public health officials and the public address the challenges posed by this new public health threat.

CDC is issuing updated interim guidance daily in response to the rapidly evolving situation.
Clinician Guidance

CDC has issued interim guidance for clinicians on identifying and caring for patients with novel H1N1, in addition to providing interim guidance on the use of antiviral drugs. Influenza antiviral drugs are prescription medicines (pills, liquid or an inhaler) with activity against influenza viruses, including novel influenza H1N1 viruses. The priority use for influenza antiviral drugs during this outbreak is to treat severe influenza illness, including people who are hospitalized or sick people who are considered at high risk of serious influenza-related complications.
Public Guidance

In addition, CDC has provided guidance for the public on what to do if they become sick with flu-like symptoms, including infection with novel H1N1. CDC also has issued instructions on taking care of a sick person at home. Novel H1N1 infection has been reported to cause a wide range of symptoms, including fever, cough, sore throat, body aches, headache, chills and fatigue. In addition, a significant number of people also have reported nausea, vomiting or diarrhea. Everyone should take everyday preventive actions to stop the spread of germs, including frequent hand washing and people who are sick should stay home and avoid contact with others in order to limit further spread of the disease.
Testing

CDC has developed a PCR diagnostic test kit to detect this novel H1N1 virus and has now distributed test kits to all states in the U.S. and the District of Columbia and Puerto Rico. The test kits are being shipped internationally as well. This will allow states and other countries to test for this new virus. This increase in testing will likely result in an increase in the number of confirmed cases of illness reported. This, combined with ongoing monitoring through Flu View should provide a fuller picture of the burden of disease in the United States over time.

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